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The BIOFIRE System and Your Immune System

The BIOFIRE System provides syndromic infectious disease testing, which allows healthcare providers to choose the right test, the first time. Patients benefit from quicker diagnosis and more targeted treatments. Clinicians benefit from improved stewardship for antibiotics. Labs gain efficiency and cost savings.

The BioFire Pneumonia Plus Panel (PN panel) analyzes native sputum (including mini-BAL), endotracheal lavage, and bronchoalveolar liquids (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials within an hour.

Respiratory

The burning of biomass, such as plants, wood and other organic materials produces gaseous pollution and fine particles that negatively affect the respiratory system. Climate change could make it more difficult to reverse the negative impacts of forest bioethanol fires on the health of humans.

In the United States wildfire smoke is linked to hospitalizations due to respiratory diseases like asthma, COPD, and lung cancer. In addition, this type of air pollution can be an important risk factor for cardiovascular diseases and a significant contributing factor to the burden of disease for the most vulnerable population which includes those who are of lower socioeconomic status (SES).

During the COVID-19 pandemic, many communities were exposed to unhealthy levels of air pollution resulting from wildfires. However the response of public health officials to this environmental issue has been limited and largely focused on educating people regarding symptom management. This knowledge gap is alarming given the evidence that smoking and other sources of air pollution can cause health problems.

Researchers are now looking at how to best protect the public's health during any future events of this kind. NIH funds research on this critical public health issue through the BLUE CORAL and FIRE CORAL studies.

For the first time the study is a prospective cohort study that will evaluate long-term effects of exposure to smoke from wildfires as well as other sources. FIRE CORAL enrolls adults who are admitted to hospital for bio Fuel Fireplace COVID-19 index episodes and speak English or Spanish but aren't pregnant. The Fire Coral protocol includes a variety of assessments in person that objectively measure the pulmonary function testing and lung imaging, as well as functional assessment.

Smoke and other particles can cause or worsen respiratory problems like emphysema COPD and pneumonia. A number of steps can be taken to avoid or reduce the adverse health effects from short-term exposures to smoke, which includes avoidance of outdoor activities whenever possible and using the EPA's "N95" mask that is designed to capture fine particles.

Smoking can cause irritation to the throat, eyes and nose. To minimize symptoms, drink plenty of water, and take medications that reduce inflammation, like corticosteroids.

Bloodstream

The bloodstream is your first line of defense against germs that invade your system. Dendritic cells, which are special cells, are like the fire department's call center; they gather antigens (molecules that trigger an immune response) from invaders and release proteins that signal other white blood cells to fight them. The total white blood cells, differentials and band cells increased after firefighters' firefighting activities as compared to levels following intense exercise without firefighting.

Skin

As the wildfires in California released smoke and ash into the air this past winter and fall dermatologists were concerned how it might affect the skin of people exposed to it. Maria Wei is a graduate student from University of California, Irvine. She examines how extreme wildfire pollution affects the skin. Her research was published on April 22, 2012 in Scientific Reports.

Wei's study shows that the temperature of the skin fluctuates according to the length of time the body is exposed. It can take as long as two hours for the skin of an individual to reach its "flash point"--the place where it begins to burn and then turn into ash. It's important not to stay near a fire pit or campfire, and you should always wear protective clothing when outdoors during a hot or humid day.

Forest fires will continue to happen, despite the precautions implemented to reduce the risk of fires from causing pollution. Wei is predicting that the number of people suffering the consequences of wildfires will increase as climate change causes more forests to be burned. That means more people will have to wear hats, long sleeves, and thick moisturizers.

It's also worth knowing that atopic dermatitis (itchy skin) that many people suffer from is often exacerbated by air pollution from wildfires. She claims that the particles in smoke can block pores which can cause skin irritation.

Another issue is the fact that atopic dermatitis can make people more sensitive to UV light, ethanol biofuel Fireplace which can be aggravated by wildfire smoke. This makes people more likely to seek out tanning salons and may cause people to tan less protection than they should.

While a ethanol fire and ice facial may help reduce the effects of atopic dermatitis it is not safe for anyone with an open wound or rash on their face. This treatment is not recommended for people who have active acne, or if you're pregnant or nursing. The IS Clinical indoor bio ethanol fire & Ice Facial at Novuskin, Las Vegas' most prestigious membership MedSpa It's a highly effective, results-driven facial that bridges the gap between a mild facial and a peel without having to wait for any downtime. It's designed to rejuvenate skin, improve rosacea and decrease fine lines and acne scarring, as well as encourage cellular regeneration. It's an incredible treatment that will give you a radiant glow.

Infections

The human body is a complicated system of organs and tissues that work to shield us from infections. Infections are caused by microscopic microorganisms like parasites, viruses, bacteria and fungi that infect healthy cells and cause them to multiply out of control. Your immune system may react by displaying symptoms of illness. These symptoms could range from a swollen or achy nose to stomach ache, Bio-Ethanol fires but they can also include a fever high swelling of the glands, an rash. The type of infection and the location can affect the severity of your symptoms.

Infections can spread in a variety of ways however the most common are from person to person by droppings that hang in the air after sneezing or coughing. Bacterial infections like strep throat, tuberculosis, meningococcal disease, and Legionnaires disease spread through this method, along with certain viral infections such as the common cold and influenza. Certain bacterial infections, such as skin infections or sexually transmitted diseases (STIs) such as Chlamydia and gonorrhea can be transmitted through direct contact with infected mucous or tissue surfaces, or indirectly by contaminated surfaces. Some bacterial infections are spread by insects, such as fleas, ticks, or mosquitoes.

The virus and the parasites are small enough to penetrate your bloodstream and infect your cells, which can cause serious illness such as the common cold and AIDS. Fungi can cause skin problems like athlete's feet and ringworm and others can infect the respiratory tract and nervous system.

The BioFire PN Panel employs our innovative FilmArray technology to detect a comprehensive list of pathogens involved in upper respiratory infections in sputum and the bronchoalveolar lavage samples. The kit comes with a reagent pouch that stores all the chemistry needed to perform reverse transcription PCR, nested PCR and detection using a single machine. It's a simple solution to aid clinicians in identifying and treat patients with a variety of respiratory symptoms. This test has been granted an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high-complexity labs.